You would save more gas if there was no wind.
you would save more gas removing your mirrors.
There is no measurable difference in size.
There is no measurable difference in 'aero' or smoothness.
IMHO I would alwys want the newest tire possible for a HOST of reasons that have nothing to do with the reasons you list.
You are reaching for the 'fruit at the very top of the 30ft tree'.
Stick to the low hanging stuff.
But if you want to think about it.....
There is only an 'optimal' point in tire wear. And that is probably at 1/2 tread. And the trade off would be so slim as to not even register.
Yeah, a slick tire is aerodynamic......so? The chance of an accident has increased exponentially.
It's useless for driving.
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