Untill recently trying to maximum MPG, I've used E10 excusively (some E85 in FFV cars) for the last 25 years, I've replaced one fuel pump (Malibu at about 200,000 miles, now 250,000) Stratus 230,000 and others to almost 200,000 no other fuel pumps or fuel related problems.
I have had to clean a few motorcycle carbs that where dirty when I bought them, but never had to mess with again running E10.
E15 has about 2% less energy than E10, I doubt many carb's are tuned that close that 2% less with make them run lean.
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