The more the power out of an engine, the more it is tuned for high rpm and that often means compromising reliability.
There are some 4 stroke on which you need to replace the piston every 12 hours (RMZ 250)
The implications of dephasing the inlet have been discussed in "Atkinsoning motorbike engine" and yes, it requires FI.
Might be more cost effective and fuel efficient than detuning an engine ...
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