I tried driving from Barstow to Flagstaff at 65 MPH last Summer instead of the 70 MPH(California)and 75 MPH(Arizona) speed limit as I drove the trip the previous two years.
Compared to the previous two years, I got 32.9 MPG vs 27.9 MPG.
The speed difference cost me 35 minutes over 350 miles.
The drive was less stressful. Yes, it was worth the extra time. I had enough fuel left over to commute to work for three days.