The hybrid system to a vehicle either improves performance or mpg. Its usually a percentage of the base mpg a similar vehicle would get. Auto stop for the honda has been studies to help mpg by 10%. Ive disabled and made sure conditions were peak for it to work. I have to agree about the % gain.
Now if you are delivering newspapers for example having a prius maybe less wear n tear as the tranny has no clutch. Its all gears. The Honda uses a clutch pack and a steel belt for the cvt. So every stop an go you got clutch engagement and the band moving up and down 2 pulleys. Usually the band breaks.
I know you are just focused on mpg, but the exhaust is also cleaner.