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Decreases in short-term memory, IQ, and altered brain metabolic ratios in urban apolipoprotein ?4 children exposed to air pollution -- ScienceDaily
"The authors argue that sustained exposures to urban air pollution result in cognitive underperformance and metabolic brain changes that reflect glial and neuronal alterations. The combined effects of residency in a highly polluted city and APOE ε4 could lead to an acceleration of neurodegenerative changes. Air pollution is a serious public health issue and exposures to concentrations of air pollutants at or above the current standards have been linked to neuroinflammation and neuropathology. In the US alone, 200 million people live in areas where pollutants such as ozone and fine particulate matter exceed the standards. There are significant associations between exposures to particulate matter and increased mortality due to stroke, cardiovascular, and respiratory events."