Most LRR tires have a poor tread pattern for snow, but that can be true of any tire. High silica content probably keeps them softer than most normal tires at low temperature so in that way they're probably superior. Most winter tires are very low rolling resistance because what makes their tread compound soft at low temperature also lowers rolling resistance.
I know it varies from vehicle to vehicle, but in the Insight, going with something other than RE92's can be worth as much as 15-20mpg. This is a car that is capable of 100mpg mind you, with excellent aerodynamics so as to make rolling resistance a relatively larger portion of energy wasted, but *if* it scaled for a Civic the same way, you'd be looking at maybe 6-8mpg at the upper end. It's likely less.
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