It's not just the cost of fuel, it's also the ongoing maintenance of everything else that needs attention due to putting miles on the chassis. When I bought my 1998.5 from DOT auction, I requested and received the full service history, which was nearly a ream of paper.
When do (quality) cars need front end rebuilds, U-joint greasing, $1000+ tire replacements, 12 quart oil changes, fuel filter changes, etc, etc.
Whenever I spend a lot of time in my sedan, it feels neat to be up high looking over traffic in the truck... and whenever I spend a lot of time in the truck, it feels neat to be down low in what feels like my sports sedan.
I'm saying that long distance commuting in a truck and asking about truck tires (still don't know if that's what you're doing, just sayin') is like asking how to better hammer nails with a shovel. It's worthwhile learning how best to hammer nails with a shovel if you're determined to do so, but it's not the prudent way to do the job.
If you're a single guy, then I get the appeal of a truck. Especially bench seats