Quote:
Originally Posted by Xist
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- that link shows photo's of a rainy weekend?
To understand why a high dose of chloroquine kills you must know what it does.
Chloroquine kills cells. It triggers
apoptosis, the orderly process in which a cell destroys its own DNA, RNA and all other reactive molecules to prevent damage to the organism once it ruptures.
A mild chloroquine dose won't trigger healthy cells but virus stricken cells will react. Apoptosis will also end virus production within the cell, reducing the spread.
Without chloroquine a virus infected cell will continue producing virus until it can function no more. It will then die (
necrosis) and rupture, releasing its virus content and reactive content infecting and damaging the cells around it.
I think chloroquine is an essential medicine but it must be used with great care.
It has been used against malaria and liver cancer (a.o.) but it is easy to see why other medicine, if available, is preferred.
Also, if a virus learns to block apoptosis then chloroquine will lose its effectiveness. Chloroquine must remain an if all else fails medicine.
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