[Ecky]

13mpg and 14mpg city? 25% worse than the pickup truck would be a tough sell for me as a daily.

What year/age range are you looking in?

I believe the RX450h can tow 3500lbs officially, and is rated for 31mpg city. The older RX400h is 27mpg city with the same tow rating. The drivetrain is essentially a scaled up version of what's in the Prius (has an electric motor in the rear so they're both AWD). I'd look closely at forums on any common failures for these specific vehicles, but I'd wager they're pretty solid.

EDIT: I'd get others opinions on towing above its rating. I tow 2000lbs behind my G1 Insight (more than the car weighs) now and then, and while I wouldn't exactly recommend it, it's alright for short distances and lower speeds. I could see it being a non-issue entirely if I had trailer brakes.