Here is a site I used for some of my initial ideas for FE improvement:
A Truck That Drinks Less Than a Car? | Popular Science
Just doing the panels outlined in this article will benefit you. I am, and can get 20 mpg nearly at will once the truck hits 4th gear. My truck is rated 14/19.
Make sure your front end alignment is correct. I discovered mine has been out of whack for a year?! Boy is that frustrating.
Lowering your truck will also help, but not dramatically. It does reduce the drag coefficient. Synthetics also help, but the kicker is reducing your truck's Cd. Speed (velocity) is the enemy, as drag increases with speed squared, not just directly with speed. See the drag equation, rearranged to solve for your Cd:
The Drag Coefficient
Drag = (1/2)*Rho*Cd*A*V*V where Rho (I don't have the greek letter key) is air density, Cd is your drag coefficient, A is your frontal area, and V is your speed (or velocity).
The factors you can really change are your speed/velocity and Cd.
As you can see, the faster we go the drag increases dramatically. My truck has a 0.52 Cd, and with 32 sq ft of frontal area (A), I am in a world of hurt for drag. I suspect your truck isn't that much better than mine.
Here's another page to look at:
Drag Force Calculation and Equations. Drag Coefficients.
[edit] rmay, when my alignment was on track I hit 24 mpg driving across northern Utah on I-80, so I agree, GMs are typically better on aero than Dodges, especially my Gen3. GM has an aeronautical engineer working high in their company, so I am sure he is influencing things...